Pharmacodynamics of doxacurium during cardiac surgery with hypothermic cardio-pulmonary bypass
نویسندگان
چکیده
منابع مشابه
Pharmacokinetics of doxacurium during normothermic and hypothermic cardiopulmonary bypass surgery.
PURPOSE To compare the pharmacokinetic behaviour of doxacurium in patients undergoing normothermic or hypothermic cardiopulmonary bypass (CPB) for coronary artery bypass graft surgery. METHODS Twenty patients in two equal groups were studied. Anaesthesia was induced with sufentanil and midazolam after a standard premedication. Doxacurium was administered at 3 x ED95 (80 micrograms.kg-1), and ...
متن کاملAcute mesenteric ischemia after cardio-pulmonary bypass surgery.
Acute mesenteric ischemia (AMI) is a highly-lethal surgical emergency. Several pathophysiologic events (arterial obstruction, venous thrombosis and diffuse vasospasm) lead to a sudden decrease in mesenteric blood flow. Ischemia/reperfusion syndrome of the intestine is responsible for systemic abnormalities, leading to multi-organ failure and death. Early diagnosis is difficult because the clini...
متن کاملPredictors for aki in a cardiac surgery population undergoing cardio-pulmonary bypass
Methods In total, 259 patients were enrolled, after the exclusion of patients with severe pre-existing renal insufficiency (defined as a eGFR< 15 ml/min). As part of a broader study, urine and blood samples were obtained immediately before initiation of cardio-pulmonary bypass. Patients were subsequently retrospectively divided into 2 groups, AKI (n=84) and non-AKI (n=175). This subdivision was...
متن کاملApplication of a pharmacokinetics-pharmacodynamics approach to the free propofol plasma levels during coronary artery bypass grafting surgery with hypothermic cardiopulmonary bypass
OBJECTIVES The objective of this study was to apply a pharmacokinetics-pharmacodynamics approach to investigate the free propofol plasma levels in patients undergoing coronary artery bypass grafting under hypothermic conditions compared with the off-pump procedure. METHODS Nineteen patients scheduled for on-pump coronary artery bypass grafting under hypothermic conditions (n=10) or the equiva...
متن کاملEmergent Cardiopulmonary Bypass during Cardiac Surgery.
During orientation to the cardiac surgery operating room, new staff may not be exposed to emergent situations. Allowing team members the opportunity to practice their roles during less common, high-stakes emergency cardiac surgical scenarios may better prepare them when crises do arise in the OR. The Emergency Cardiopulmonary Bypass Course was developed to meet the needs of new staff starting i...
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ژورنال
عنوان ژورنال: Canadian Journal of Anaesthesia
سال: 1996
ISSN: 0832-610X,1496-8975
DOI: 10.1007/bf03011254